Acuaiss Ultra moisturising drops is a sterile, viscoelastic and hypotonic preservative-free solution in multidose format. It contains hyaluronic acid, which provides prolonged relief for dry,tired and stressed eyes
Preservative- free multidose containing a special
biomolecule of hyaluronic acid
Deliver Spain Quality
Use up to 300 drops
Preservative-FREE
Valid for 90 days
- It moisturizes the eye, providing instant relief for the symptoms of dry eyes and making contact lenses easier to handle.
- It lubricates the contact lens which reduces the effect of the eyelid rubbing on the lens when blinking. In other words, using hyaluronic acid is like greasing machinery to reduce friction for smooth running. This is crucial considering we unconsciously blink every 5 seconds.
- It envelops the lens, protecting it from oily deposits. This hyaluronic acid coating makes the contact lens react better to water and repel any remnants of lipids or cosmetics.
- It prevents calcium from building up on the lens as the formula contains EDTA, a chelate agent that “captures” calcium ions.
- It is free from preservatives thanks to its OSD system, which seals the content against external microbial contamination and dispenses the exact amount of product.
- Acuaiss Ultra comes in a 10 ml bottle which guarantees 250 uses. This format is much more practical and affordable than the single-dose alternative, which is designed to be disposed of after one use.
METHOD OF USE
TEAR FILIM VICOSITY
The link between the molecular weight of the hyaluronic acid in an artificial tear and tear film viscosity.
The tear film has viscoelastic properties, i.e. it is viscous when the eye is open and becomes fluid when the eyelid closes. To achieve this effect, artificial tears should imitate the behaviour of natural tears as closely as possible. Hyaluronic acid has those same properties, which together with its ability to store water, make it the ideal component in formulas intended to keep the eye hydrated.
Hyaluronic acid is a polymer distributed in chains. It can be produced with different molecular weights, which depend on the length of those chains:
Low molecular weight HA: approximately 50,000 Daltons
Medium molecular weight HA: approximately 300,000 Daltons
High molecular weight HA: approximately 1,000,000 Daltons
The higher the molecular weight of the hyaluronic acid used, the greater its viscoelastic properties will be and the longer it will remain in the eye. Greater viscosity means more comfort.
The graph below shows the viscosity of various hyaluronic acid solutions with different molecular weights crossed with the shear stress that is caused when blinking. It is clear from the graph that the higher the molecular weight, the greater the viscosity when the eye is open.
Another variable to be borne in mind is the concentration of HA, which also affects hydration. Furthermore, high concentrations of HA have been linked to patients experiencing blurred vision. It has therefore been found that concentrations of 0.10 to 0.20% provide a sufficient degree of hydration, and that increasing that concentration does not improve hydration but can cause blurred vision.
It is advisable to use high molecular weight hyaluronic acid in formulations that are intended to ease the symptoms of dry eye syndrome as it helps keep the artificial tear in the eye for longer, thus enhancing its efficacy and making it more comfortable.
Acuaiss Ultra Moisturizing Drops contain very high molecular weight hyaluronic acid (2,000,000 Daltons) at a concentration of 0.15%, which guarantees the viscosity of the tear film without causing blurred vision, ensuring maximum hydration.
Recommendation
Target User
- For contact lens wearers with problems caused by dry eyes
- For daily contact lens users.
- For people with eye conditions caused by contact lens friction when blinking
- For people who are sensitive to preservatives
- Indicated in cases of mild dry eye caused by adverse environmental circumstances (exposure to air-conditioning, heating, etc.).
- Computer Vision Syndrome, since the low blinking frequency, impairs tear quality and renders the use of specific moisturizers necessary.
- People on long-term treatments who may eventually develop preservative intolerance.
- People already presenting an eye condition that renders them particularly sensitive to preservatives.
- Age-related chronic dry eye. Contact lens wearers. People who prefer high-quality preservative-free products.
- People with dry eye symptoms related to hormonal disorders, pregnancy, treatment with certain drugs, who have had surgical interventions or cataract surgery
Features
What does a hyaluronic acid biomolecule do?
1) It provides very high viscosity
- To restore the tear film’s stability, high viscosity is required when the eye is open and fluidity when it closes during blinking.
- The higher the molecular weight of the hyaluronic acid, the greater the consistency of the tear during the rest phase and the greater the sensation of comfort.
- The hyaluronic acid biomolecule present in Acuaiss Ultra has a high molecular weight (2 million Daltons)
2) It helps to make the formula similar to the composition of the human tears
3) Slightly hypotonic formula-
- Acuaiss Ultra is slightly hypotonic in order to balance the greater concentration of salts present in an unstable tear film.
Long-lasting moisturization
Because hyaluronic acid is an excellent moisturizer
- It has great water retention capacity.
- It remains in the eye for longer than other moisturizing drops.
- It increases TBUT. (Tear Beak-up Time)
Because hyaluronic acid has a regenerating action
- Hyaluronic acid has a healing effect on the corneal epithelium, since it binds to the CD44 receptor, promoting the epithelial cell proliferation
- Hyaluronic acid provides a long-lasting effect as the corneal epithelium contains CD44 receptors (glycoproteins) that recognise and bind to the HA molecule.
- This ensures it will remain in the eye for longer than other moisturizing drops, which are more quickly eliminated through the lacrimal sac.
High molecular weight hyaluronic acid biomolecule
Hyaluronic acid is a biological molecule that is naturally found in the human eye.
- Acuaiss Ultra contains a type of hyaluronic acid with a very high molecular weight (1.6 million Daltons) in exactly the right measure (0.15%) to boost hydration without blurring vision.
- Therefore, optimal viscoelasticity levels are achieved thanks to the high molecular weight of this biomolecule.
- The higher the molecular weight, the longer the chain and, consequently, the greater the viscosity when the eye is resting, i.e. when open.
- This means it will last longer inside the eye.
- Lower viscosity levels when blinking allow the liquid to spread more evenly across the surface of the eye.
- The hyaluronic acid used in this formula is biocompatible and of the highest purity.
Special OSD Bottle
A bottle design that enables us to use preservative-free formulas
The bottle containing Acuaiss Ultra Moisturizing Drops is designed to protect its contents from external contamination
The OSD bottle protects its contents from external microbes thanks to a filter that prevents contaminated air from coming into contact with the liquid inside. This is possible because the OSD system features separate circuits to let air into the bottle and let liquid out.
The liquid is dispensed through the dropper due to the pressure created when squeezing the bottle. Once the drop has formed, an inner device shuts the system to prevent microorganisms from entering through the dropper.
But the OSD bottle needs an air inlet in order to recover its shape. That air flows in through a side circuit that is physically separate from the liquid outlet, and passes through a sterilising filter.
How the mechanism works:
1. When the bottle is tipped upsidedown, no drops are released thanks to the pressure of the spring covering the outlet.
2. By pressing the device, the spring recoils allowing a drop to form at the outlet.
3. Once the liquid drops, the user releases the bottle allowing the spring to return to its position and cover the outlet once again.
4. As the bottle is restored to its initial shape, air is sucked in through the inlet at the side (which is separate from the liquid outlet).
The air passes through a filtering membrane that prevents the content of the bottle from being contaminated. This unique system is extremely safe and hygienic. Holes in the lid allow any remnants of liquid around the dropper to evaporate before becoming contaminated.The system also makes the drops easy to apply compared to other preservative free options on the market.
Biocompatible formula
- Acuaiss Ultra contains a biological phosphate buffer that makes for stable, physiological pH levels.
- The hyaluronic acid used in the formula is biocompatible (meaning the molecule is naturally present in the human eye) and extremely pure.
- The Acuaiss Ultra formula is mildly hypertonic to balance the high salt concentration that builds up in dry eyes.
Composition
DESCRIPTION
0.15% sodium hyaluronate, sodium chloride, disodium phosphate, monosodium phosphate, edetate disodium, and purified water
Acuaiss Ultra moisturizing drops are preservative-free artificial tears that come in a 10 ml bottle. They contain a biomolecule of hyaluronic acid.
Formulated to provide long-lasting relief for people with dry, tired or strained eyes.
“This content references Aptar Pharma’s Ophthalmic Squeeze Dispenser (OSD) as featured in their original video [YouTube link], used here solely for educational and informational purposes. All trademarks and visual assets remain the property of their respective owners.”